1239915-58-2Relevant academic research and scientific papers
An efficient synthesis of polysubstituted pyrroles via copper-catalyzed coupling of oxime acetates with dialkyl acetylenedicarboxylates under aerobic conditions
Tang, Xiaodong,Huang, Liangbin,Qi, Chaorong,Wu, Wanqing,Jiang, Huanfeng
, p. 9597 - 9599 (2013/10/08)
A Cu-catalyzed [3+2]-type condensation reaction of oxime acetates and dialkyl acetylenedicarboxylates that provides highly substituted pyrroles under aerobic conditions is described. The newly formed pyrroles are easily employed for further transformations to prepare pyrrolo[2,1-a]isoquinoline skeletons. The Royal Society of Chemistry 2013.
Addition/cycloaddition of acetylenedicarboxylates to open-chain or cyclic amino carbonyl compounds
Guerrini, Giacomo,Ponticelli, Fabio
experimental part, p. 3919 - 3926 (2010/10/19)
Some new, interesting, and unknown heterocyclic rings and open-chain molecules have been obtained with ease and under mild conditions by reaction of a wide range of amino carbonyl compounds with acetylenic esters. The reactivity is highly dependent on the substituents and their positions in the starting material, which can be either cyclic (pyrazolones) or open-chain compounds.
