1239957-22-2

Basic information

• Product Name: tert-butyl 4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)piperidine-1-carboxylate
• Synonyms: tert-butyl 4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)piperidine-1-carboxylate
• CAS NO: 1239957-22-2
• Molecular Weight: 574.159
• Mol File: 1239957-22-2.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl 4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)piperidine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)piperidine-1-carboxylate(1239957-22-2)
• EPA Substance Registry System: tert-butyl 4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)piperidine-1-carboxylate(1239957-22-2)

Safety Data

• Hazardous Substances Data: 1239957-22-2(Hazardous Substances Data)

Upstream product

• 1239963-85-9 5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazole-2-thiol 
• 158407-04-6 tert-butyl 4-(bromomethyl)piperidine-1-carboxylate 
• 1239963-83-7 1-amido-3-(4-chloro-3-methoxyphenyl)-3-methyl-2-methylbutan-2-one hydrochloride 
• 1239963-82-6 1-azido-3-(4-chloro-3-methoxyphenyl)-3-methyl-2-methylbutan-2-one 
• 1239963-79-1 2-(4-chloro-3-methoxyphenyl)-N-methoxy-N,2-dimethylpropanamide 
• 1239963-81-5 1-bromo-3-(4-chloro-3-methoxyphenyl)-3-methyl-2-methylbutan-2-one 
• 1239963-78-0 2-(4-chloro-3-methoxyphenyl)-2-methylpropanoic acid 
• 1239963-80-4 3-(4-chloro-3-methoxyphenyl)-3-methyl-2-methylbutan-2-one 
• 850564-15-7 2-(4-Chloro-3-methoxy-phenyl)-2-methyl-propionitrile 

Downstream Products

• 1239963-62-2 4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)piperidine 
• 1239957-23-3 4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylthio)methyl)-1-(methylsulfonyl)piperidine 
• 1239957-24-4 4-((5-(2-(4-chloro-3-methoxyphenyl)propan-2-yl)-1-(4-fluorophenyl)-1H-imidazol-2-ylsulfonyl)methyl)-1-(methylsulfonyl)piperidine 

Relevant articles and documents

TRIAZOLE AND IMIDAZOLE DERIVATIVES FOR USE AS TGR5 AGONISTS IN THE TREATMENT OF DIABETES AND OBESITY

The present invention comprises TGR5 agonists of structural formula I, wherein X, R1, R2, and R5 are defined herein, as well as N-oxides of them and pharmaceutically acceptable salts thereof. The invention further comprise