1240035-65-7

Upstream product

• 545-06-2 trichloroacetonitrile 

Downstream Products

• 1240035-68-0 Fmoc-Thr(β-2F-Bn3Gal-(1->3)-α-4,6-O-Bzn-GalNAc)-OtBu 
• 1321826-37-2 N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6-fluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester 
• 1321826-42-9 N-(9H-fluoren-9-yl)-methoxycarbonyl-O-(2-acetamido-2,6-dideoxy-6,6-difluoro-3-O-[3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranosyl]-α-D-galactopyranosyl)-L-threonine tert-butyl ester 
• 1393355-26-4 2-deoxy-2-fluoro-3,4,6-tri-O-benzyl-β-D-galactopyranosyl-(1->1)-(2S,3R,E)-2-amino-3-O-benzyl-4-octadecene-1,3-diol 
• 1393355-27-5 2-deoxy-2-fluoro-3,4,6-tri-O-benzyl-β-D-galactopyranosyl-(1->1)-(2S,3R,E)-2-octadecanamido-3-O-benzyl-4-octadecene-1,3-diol 
• 1393355-19-5 methyl (2-deoxy-2-fluoro-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1->6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside 
• 1393355-13-9 methyl (2-deoxy-2-fluoro-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-α-D-glucopyranoside 
• 1393355-11-7 methyl (2-deoxy-2-fluoro-3,4,6-tri-O-benzyl-α-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-α-D-glucopyranoside 
• 1393354-80-7 methyl (2-deoxy-2-fluoro-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1->3)-2-O-benzyl-4,6-O-benzylidene-α-D-glucopyranoside 
• 1393354-65-8 1-O-allyl-3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranose 
• 1393354-05-6 1-O-isopropyl-3,4,6-tri-O-benzyl-2-deoxy-2-fluoro-β-D-galactopyranose 
• 1393354-75-0 methyl (2-deoxy-2-fluoro-3,4,6-tri-O-benzyl-β-D-galactopyranosyl)-(1->3)-2-O-benzyl-4,6-O-benzylidene-α-D-galactopyranoside 
• 1393354-74-9 methyl (2-deoxy-2-fluoro-3,4,6-tri-O-benzyl-α-D-galactopyranosyl)-(1->3)-2-O-benzyl-4,6-O-benzylidene-α-D-galactopyranoside 
• 1393355-25-3 2-deoxy-2-fluoro-3,4,6-tri-O-benzyl-β-D-galactopyranosyl-(1->1)-(2S,3R,E)-2-azido-3-O-benzyl-4-octadecene-1,3-diol 

Relevant academic research and scientific papers

Comparative Analysis of Fluorine-Directed Glycosylation Selectivity: Interrogating C2 [OH → F] Substitution in d- Glucose and d- Galactose

The influence of C2 [OH → F] substitution on the stereochemical course of chemical glycosylation was interrogated in both D-glucose and its C4 epimer D-galactose. Molecular editing at C2 and configurational inversion at C4 were simultaneously investigated

Fluorinated glycosyl amino acids for mucin-like glycopeptide antigen analogues

The aberrant glycosylation profiles of mucin glycoproteins on epithelial tumour cells represent attractive target structures for the development of immunotherapy against cancer. Mucin-type glycopeptides have been successfully investigated as molecularly defined vaccine prototypes for triggering humoral immunity but are susceptible to rapid in vivo degradation. As a potential means to enhance the bioavailabilities of the antigenic structures, hydrolysis-resistant carbohydrate analogues with fluorine substituents at positions C6, C2′ and C6′ were synthesised and incorporated into the tandem repeat sequence of the mucin MUC1. The resulting pseudo-glycopeptides can be used to elucidate the effects of chemically modified antibody determinants on metabolic and immunological properties.