1240050-25-2Relevant academic research and scientific papers
An efficient synthesis of highly functionalized 4H-pyrano[3,2- d ]isoxazoles via isocyanide-based three-component reaction
Esmaeili, Abbas Ali,Hosseinabadi, Rahele,Habibi, Azizollah
experimental part, p. 1477 - 1480 (2010/08/19)
We present a novel, convenient, and efficient method for synthesizing polysubstituted 4H-pyrano[3,2-d]isoxazoles based on a three-component reaction. The zwitterions generated from the reaction of isocyanides and dialkyl acetylenedicarboxylates are reacted with 3-phenylisoxazol-4-(5H)-one to produce the title compounds in good yield.
