1240259-25-9Relevant academic research and scientific papers
Synthesis of DNA with spirobenzopyran as an internal covalent modification
Beyer, Christoph,Wagenknecht, Hans-Achim
experimental part, p. 1371 - 1376 (2010/08/22)
The photochromic spirobenzopyran was incorporated as an internal modification into oligonucleotides by two different synthetic strategies: For the first route the spiropyran phosphoramidite was synthesized as a DNA building block, whereas for the second route the postsynthetic click-type ligation was applied. Photoinduced ring opening of the chromophore could not be achieved in duplex DNA.
