1240314-99-1Relevant academic research and scientific papers
Direct experimental evidence for the priority of flexible ligand skeleton in asymmetric friedel-crafts alkylation of indole with nitroalkenes
Liu, Han,Wang, Neng-Dong,Du, Da-Ming
experimental part, p. 114 - 120 (2010/08/20)
Direct experimental evidence for the priority of flexible ligand skeleton in asymmetric Friedel-Crafts alkylation was obtained through XRD analysis of flexible ligand/ZnCl2 complex, as well as synthesis of dihydroacridine-linked bis(oxazoline) ligands with planar rigid scaffold. A transition state model without NH φ interaction was proposed for the rigid ligands to interpret the inversion of absolute configuration.
