124038-36-4

Basic information

• Product Name: Benzoic acid, 3-(1,3-dioxolan-2-yl)-, methyl ester
• Synonyms: Methyl 3-(1,3-dioxolan-2-yl)benzoate;Methyl 3-(1,3-dioxolan-2-yl)benzoate ,97%;Benzoic acid, 3-(1,3-dioxolan-2-yl)-, methyl ester
• CAS NO: 124038-36-4
• Molecular Formula: C₁₁H₁₂O₄
• Molecular Weight: 208.21
• Mol File: 124038-36-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzoic acid, 3-(1,3-dioxolan-2-yl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-(1,3-dioxolan-2-yl)-, methyl ester(124038-36-4)
• EPA Substance Registry System: Benzoic acid, 3-(1,3-dioxolan-2-yl)-, methyl ester(124038-36-4)

Safety Data

• Statements: 36/37
• Safety Statements: 26-37/39
• Hazardous Substances Data: 124038-36-4(Hazardous Substances Data)

Usage

Chemical Properties

Yellow liquid

Upstream product

• 52178-50-4 Methyl 3-formylbenzoate 
• 107-21-1 ethylene glycol 
• 1708-41-4 2-(furan-2-yl)-1,3-dioxolane 
• 292638-85-8 acrylic acid methyl ester 
• 6192-52-5 p-toluenesulfonic acid monohydrate 

Downstream Products

• 836684-59-4 3-(3-[1,3]dioxolan-2-yl-phenyl)-3-oxo-propionitrile 
• 140639-94-7 2-(3'-hydroxymethyl)phenyl-1,3-dioxolane 

Relevant articles and documents

A Combined Experimental–Theoretical Study on Diels-Alder Reaction with Bio-Based Furfural: Towards Renewable Aromatics

The synthesis of relevant renewable aromatics from bio-based furfural derivatives and cheap alkenes is carried out by using a Diels-Alder/aromatization sequence. The prediction and the control of the ortho/meta selectivity in the Diels-Alder step is an important issue to pave the way to a wide range of renewable aromatics, but it remains a challenging task. A combined experimental-theoretical approach reveals that, as a general trend, ortho and meta cycloadducts are the kinetic and thermodynamic products, respectively. The nature of substituents, both on the dienes and dienophiles, significantly impacts the feasibility of the reaction, through a modulation on the nucleo- and electrophilicity of the reagents, as well as the ortho/meta ratio. We show that the ortho/meta selectivity at the reaction equilibrium stems from a subtle interplay between charge interactions, favoring the ortho products, and steric interactions, favoring the meta isomers. This work also points towards a path to optimize the aromatization step.

COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY

The present invention relates to compounds acting both as muscarinic receptor antagonists and beta2 adrenergic receptor agonists, to processes for their preparation, to compositions comprising them, to therapeutic uses and combinations with other pharmaceutical active ingredients.

5-MEMBERED HETEROCYCLE-BASED P38 KINASE INHIBITORS

Provided are 5-membered heterocycle-based p38 kinase inhibitors. Further provided are pyrazole and imidazole-based p38 kinase, including p38α and p38β kinase, inhibitors. Pharmaceutical compositions containing the compounds are also provided. Methods of u