Cas 1240390-40-2,dichlorobis(N<sup>(4)</sup>-methyl-4-nitroacetophenone thiosemicarbazone)manganese(II)

1240390-40-2

Post Buying Request

Basic information

Product Name: dichlorobis(N⁽⁴⁾-methyl-4-nitroacetophenone thiosemicarbazone)manganese(II)
Synonyms:
CAS NO:1240390-40-2
Molecular Formula:
Molecular Weight: 630.438
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: dichlorobis(N⁽⁴⁾-methyl-4-nitroacetophenone thiosemicarbazone)manganese(II)(CAS DataBase Reference)
NIST Chemistry Reference: dichlorobis(N⁽⁴⁾-methyl-4-nitroacetophenone thiosemicarbazone)manganese(II)(1240390-40-2)
EPA Substance Registry System: dichlorobis(N⁽⁴⁾-methyl-4-nitroacetophenone thiosemicarbazone)manganese(II)(1240390-40-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1240390-40-2(Hazardous Substances Data)

Suppliers
Usage
Upstream product
Downstream Products
Article

1240390-40-2 Suppliers

Recommended suppliers

1240390-40-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1240390-40-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,0,3,9 and 0 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1240390-40:
(9*1)+(8*2)+(7*4)+(6*0)+(5*3)+(4*9)+(3*0)+(2*4)+(1*0)=112
112 % 10 = 2
So 1240390-40-2 is a valid CAS Registry Number.

1240390-40-2Upstream product

72488-46-1 N^(4-)methyl-4-nitroacetophenone thiosemicarbazone

1240390-40-2Downstream Products

1240390-40-2Relevant academic research and scientific papers

Manganese(II) complexes with N4-methyl-4-nitrobenzaldehyde, N4-methyl-4-nitroacetofenone, and N4-methyl-4- nitrobenzophenone thiosemicarbazone: Investigation of in vitro activity against Trypanosoma cruzi

Batista, Denise Da Gama Jaén,Da Silva, Patrícia Bernardino,Lachter, Daniela R.,Silva, Renata S.,Aucelio, Ricardo Q.,Louro, Sonia R.W.,Beraldo, Heloisa,Soeiro, Maria De Nazaré C.,Teixeira, Letícia R.

, p. 2232 - 2238 (2011/01/05)

Thiosemicarbazones are known to be active against different pathogenic microorganisms including Trypanosoma cruzi, the etiological agent of Chagas disease. In the search for new therapeutic drugs against this illness, the complexes [Mn(H4NO2Fo4M)2Cl2] (1), [Mn(H4NO2Ac4M)2Cl2] (2) and [Mn(H4NO 2Bz4M)2Cl2] (3) of N4-methyl-4- nitrobenzaldehyde thiosemicarbazone (H4NO2Fo4M), N 4-methyl-4-nitroacetophenone thiosemicarbazone (H4NO2Ac4M) and N4-methyl-4-nitrobenzophenone thiosemicarbazone (H4NO 2Bz4M) were obtained and screened in vitro against bloodstream and intracellular forms of T. cruzi. H4NO2Fo4M, H4NO2Ac4M and their Mn(II) complexes displayed poor effect on bloodstream trypomastigotes, with IC50 values ranging from 68 to >200 μM. However, although H4NO2Bz4M was also not active, its corresponding Mn(II) complex presented high effect on this T. cruzi form, with an IC50 value of 19 μM. The effect of complex (3), against trypomastigotes of T. cruzi supports further in vitro as well as in vivo studies.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 1240390-40-2