124041-02-7Relevant academic research and scientific papers
Design, synthesis and anticonvulsant activity evaluation of 7-substituted -[1,2,4]-triazolo[4,3-f]pyrimidine derivatives
Guan, Li-Ping,Yan, Zheng-Shun,Tong, Guo-Zhong,Qu, You-Le,Sui, Xin,Chang, Yue
, p. 1076 - 1083,8 (2012/12/12)
In this study, a novel series of 7-substituted-[1,2,4]triazolo[4,3-f] pyrimidine derivatives was synthesized as potential anticonvulsant agents. Their anticonvulsant activities were evaluated by the maximal electroshock (MES) test, and their neurotoxiciti
MODULATORS FOR AMYLOID BETA
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Page/Page column 39, (2009/09/07)
The invention relates to compounds of formula wherein the substituents are as described in claim 1. Compounds of formula I are modulators for amyloid beta and thus, they may be useful for the treatment or prevention of a disease associated with the deposi
Molecular design, synthesis, and hypoglycemic and hypolipidemic activities of novel pyrimidine derivatives having thiazolidinedione
Lee, Hong Woo,Bok, Young Kim,Joong, Bok Ahn,Sung, Kwon Kang,Lee, Jung Hwa,Jae, Soo Shin,Soon, Kil Ahn,Lee, Sang Joon,Seung, Soo Yoon
, p. 862 - 874 (2007/10/03)
We previously reported the synthesis and biological activity of novel substituted pyridines and purines having thiazolidinedione with hypoglycemic and hypolipidemic activities. We now report the synthesis and antidiabetic activity of novel substituted pyr
