1240425-41-5Relevant academic research and scientific papers
Copper-in-charcoal-catalyzed, tandem one-pot diazo transfer-click reactions
Lee, Ching-Tien,Huang, Shenlin,Lipshutz, H. Bruce
supporting information; experimental part, p. 3139 - 3142 (2010/04/06)
Copper-in-charcoal (Cu/C) is an effective heterogeneous catalyst for tandem diazo transfer/click reactions. In the presence of Cu/C, various azides can be generated in situ from the corresponding amines, and subsequently undergo [3+ 2] cycloaddition with terminal alkynes to afford triazoles in good yields. The catalyst is also easily recycled.
