1240504-54-4

Basic information

• Product Name: 2-[(1-benzyl-5-oxo-2-phenyl-4-trifluoromethyl-4,5-dihydroimidazol-4-yl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile
• CAS NO: 1240504-54-4
• Molecular Weight: 508.567
• Mol File: 1240504-54-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[(1-benzyl-5-oxo-2-phenyl-4-trifluoromethyl-4,5-dihydroimidazol-4-yl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(1-benzyl-5-oxo-2-phenyl-4-trifluoromethyl-4,5-dihydroimidazol-4-yl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile(1240504-54-4)
• EPA Substance Registry System: 2-[(1-benzyl-5-oxo-2-phenyl-4-trifluoromethyl-4,5-dihydroimidazol-4-yl)amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile(1240504-54-4)

Safety Data

• Hazardous Substances Data: 1240504-54-4(Hazardous Substances Data)

Upstream product

• 15421-92-8 N-benzylbenzamidine 
• 23917-22-8 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carbonitrile 

Relevant articles and documents

Modification of biologically active amides and amines with fluorine-containing heterocycles: 2*. N-(2-thienyl)imines on the base of methyl trifluoropyruvate in cyclocondensation with 1,3-N, N-binucleophiles

An approach to the modification of the biologically active compounds, substituted 2-aminothiophenes, with fluorine-containing five-membered heterocycles is proposed. The reaction of 2-aminothiophenes with methyl trifluoropyruvate yields the corresponding N-(2-thienyl)imines, their subsequent cyclocondensation with 1,3-N,N-binucleophiles (2-aminothiazoline and benzamidines) furnished 5-oxo-6-trifluoromethyl-2,3,5,6- tetrahydroimidazothiazoles and 5-oxo-2-phenyl-4-trifluoromethyl-4,5-dihydro-1 H-imidazoles.