1240565-06-3Relevant articles and documents
MACROCYCLIC SULFONYLUREA DERIVATIVES USEFUL AS NLRP3 INHIBITORS
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Page/Page column 131, (2021/02/26)
The present invention relates to macrocyclic compounds, such as macrocyclic sulfonyl ureas. The present invention further relates to associated salts, solvates, prodrugs and pharmaceutical compositions and to the use of such compounds in the treatment and
NOVEL COMPOUNDS
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Page/Page column 166; 167, (2019/11/19)
The present invention relates to substituted 5-membered nitrogen containing heteroaryl compounds, such as sulfonyl triazoles, where the heteroaryl ring is further substituted, optionally via a linking group such as -NH-, with a cyclic group which in turn is substituted at the α-position. The present invention further relates to associated salts, solvates, prodrugs and pharmaceutical compositions, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.
Syntheses of 1-substituted-3-aminopyrazoles
Ji, Nan,Meredith, Erik,Liu, Donglei,Adams, Christopher M.,Artman III, Gerald D.,Jendza, Keith C.,Ma, Fupeng,Mainolfi, Nello,Powers, James J.,Zhang, Chun
experimental part, p. 6799 - 6801 (2011/03/18)
A series of 1-substituted-3-aminopyrazoles were prepared via Chan-Lam coupling reactions, alkylation, and pyrazole ring formation.