1240589-51-8

Basic information

• Product Name: 5R)-5-Methyl-2-Piperazinone
• Synonyms: 5R)-5-Methyl-2-Piperazinone;(5R)-5-methylpiperazin-2-one
• CAS NO: 1240589-51-8
• Molecular Formula: C5H10N2O
• Molecular Weight: 114.1457
• EINECS: -0
• Mol File: 1240589-51-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5R)-5-Methyl-2-Piperazinone(CAS DataBase Reference)
• NIST Chemistry Reference: 5R)-5-Methyl-2-Piperazinone(1240589-51-8)
• EPA Substance Registry System: 5R)-5-Methyl-2-Piperazinone(1240589-51-8)

Safety Data

• Hazardous Substances Data: 1240589-51-8(Hazardous Substances Data)

Usage

General Description

The chemical 5R)-5-Methyl-2-Piperazinone, also known as R(-)-5-Methyl-2-Piperazinone, is a heterocyclic compound that contains a piperazine ring and a methyl group. It is commonly used as a building block in the synthesis of pharmaceutical compounds and agrochemicals. This chemical is often employed in the production of various drugs, including antipsychotic and antiviral medications. Its unique structure and reactivity make it a valuable intermediate for the preparation of diverse organic compounds. Additionally, it has potential applications in research and development for the synthesis of novel pharmaceuticals and other biologically active molecules.

Upstream product

• 105-36-2 ethyl bromoacetate 
• 78-90-0 1,2-diaminopropan 

Downstream Products

• 1627749-02-3 (S)-tert-butyl 2-methyl-5-oxopiperazine-1-carboxylate 
• 1627749-02-3 (R)-tert-butyl 2-methyl-5-oxopiperazine-1-carboxylate 

Relevant articles and documents

Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering

The propensity for cancer cells to accumulate additional centrosomes relative to normal cells could be exploited for therapeutic benefit in oncology. Following literature reports that suggested TNKS1 (tankyrase 1) and PARP16 may be involved with spindle s

PYRIDAZINONES AND METHODS OF USE THEREOF

Disclosed are compounds according to Formula (A), and related tautomers and pharmaceutical compositions. Also disclosed are therapeutic methods, e.g., of treating kidney diseases, using the compounds of Formula (A).

COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF

Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.