124070-47-9

Upstream product

• 66-99-9 β-naphthaldehyde 
• 4104-47-6 N-sulfinyl-p-toluenesulfonamide 
• 1730-25-2 allylmagnesium bromide 
• 70-55-3 toluene-4-sulfonamide 
• 17692-84-1 N-(2-naphthylidene)-4-methylbenzenesulfonamide 
• 762-72-1 allyl-trimethyl-silane 
• 17692-84-1 2-naphthyl N-tosyl imine 

Downstream Products

• 1338441-73-8 2-methyl-6-(naphthalen-2-yl)-4-(p-tolyl)pyridine 
• 1338441-51-2 (E)-4-methyl-N-(1-(naphthalen-2yl)-5-oxohex-3-en-1-yl)benzenesulfonamide 

Relevant academic research and scientific papers

Palladium pincer-complex catalyzed allylation of tosylimines by potassium trifluoro(allyl)borates

(Chemical Equation Presented) Palladium pincer complex 1 catalyzes the reaction of trifluoro(allyl)borate 2 with a wide range of tosylimines (3) under mild and neutral reaction conditions. This catalytic transformation affords homoallylic amines (4) in good to excellent yield. Mechanistic studies suggest that a transmetalation reaction between complex 1 and the borate salt 2 provides an η1-allylpalladium complex, which subsequently reacts with the imine substrate.

Assembly of homoallylamine derivatives through iron-catalyzed three-component sulfonamidoallylation reaction

An efficient FeCl3-catalyzed three-component reaction between aldehydes, sulfonamides and allylsilanes has been achieved, which provides a convenient, atom-economic and green way to construct homoallylamine derivatives. In addition, this reaction exhibits excellent syn stereoselectivity with γ-substituted allylsilanes. A practical three-component cascade process to homoallylamine derivatives is reported, which uses cheap and environmentally benign FeCl3 as catalyst and shows excellent syn stereoselectivity with γ-substituted allylsilanes.