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124072-84-0

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124072-84-0 Usage

General Description

(S)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-4-ONE, also known as GRN-529, is a chemical compound that acts as a selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5). It has been studied for its potential therapeutic applications in the treatment of various neurological and psychiatric disorders, including fragile X syndrome, autism, and addiction. By blocking the activity of mGluR5, (S)-HEXAHYDRO-PYRROLO[1,2-A]PYRAZIN-4-ONE is believed to modulate glutamate signaling in the brain, which may have beneficial effects on synaptic plasticity, neurotransmission, and neuronal function. Research on this compound continues to explore its potential as a novel pharmacological agent for the treatment of these and other related conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 124072-84-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,0,7 and 2 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 124072-84:
(8*1)+(7*2)+(6*4)+(5*0)+(4*7)+(3*2)+(2*8)+(1*4)=100
100 % 10 = 0
So 124072-84-0 is a valid CAS Registry Number.

124072-84-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name (8aS)-2,3,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-4-one

1.2 Other means of identification

Product number -
Other names 6(S)-2-Oxo-1,4-diazabicyclo[4.3.0]nonane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:124072-84-0 SDS

124072-84-0Upstream product

124072-84-0Downstream Products

124072-84-0Relevant articles and documents

New Histidyl amino acid derivatives, and pharmaceutical composition comprising the same

-

, (2008/06/13)

A compound of the formula: STR1 wherein R1 is lower alkyl optionally substituted with a substituent selected from the group consisting of acyl, hydroxy, lower alkoxy, aryl, lower alkylthio and a group of the formula: STR2 in which R5 is hydrogen or acyl and R6 is hydrogen or lower alkyl; aryl; or amino optionally substituted with substituent(s) selected from the group consisting of lower alkyl and acyl; and R2 is hydrogen or lower alkyl; or R1 and R2 are taken together with the attached nitrogen atom to form a heterocyclic group optionally substituted with substituent(s) selected from the group consisting of lower alkyl, hydroxy(lower )alkyl, lower alkoxy(lower)alkyl, acyl(lower)alkyl, oxo and acyl; R3 is hydrogen or lower alkyl; and R4 is lower alkyl; and its pharmaceutically acceptable salt, processes for the preparation thereof and pharmaceutical composition comprising the same.

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