1240913-10-3Relevant academic research and scientific papers
New hypervalent iodine reagents for electrophilic trifluoromethylation and their precursors: Synthesis, structure, and reactivity
Niedermann, Katrin,Welch, Jan M.,Koller, Raffael,Cvengro, Ján,Santschi, Nico,Battaglia, Philip,Togni, Antonio
experimental part, p. 5753 - 5761 (2010/09/18)
Several new five- and a six-membered heterocyclic monochloroiodanes, including two cationic species, were synthesized. Three of which were used for the preparation of corresponding trifluoromethylation reagents. These compounds were characterized by X-ray crystallography for a comparative structural study. A reactivity study on the trifluoromethylation of para-toluenesulfonic acid has been conducted in order to compare initial rates. Compounds having a longer I-O bond display a higher reactivity.
