1241072-49-0Relevant academic research and scientific papers
Chiral zirconium complex as bronsted base catalyst in asymmetric directtype mannich reactions
Kobayashi, Shu,Salter, Matthew M.,Yamazaki, Yumi,Yamashita, Yasuhiro
experimental part, p. 493 - 495 (2010/09/06)
Asymmetric direct-type Mannich reaction using a chiral zirconium complex as Bronsted base is demonstrated. Zirconium complexes prepared from Zr(OtBu) and 3, 3′-disubstituted BINOL are found to be good catalysts in the reactions of an iminoester with malonates, and high enantioselectivities are obtained. (Chemical equation presented).
