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124168-73-6

MMP Inhibitor I, also known as GM 6001 or Ilomastat, is an effective and broad-spectrum matrix metalloproteinase (MMP) inhibitor. It is a chemical compound that can inhibit all known MMPs due to its chelating effect on the zinc ion in the active site of MMPs. This ability to inhibit MMP-induced breakdown of the extracellular matrix makes it a valuable tool in various biomedical research fields, particularly in understanding MMPs' role in cancer, wound healing, and tissue remodeling.

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  • D-Alaninamide,N-(4-aminobenzoyl)glycyl-L-prolyl-D-leucyl-N-hydroxy-

    Cas No: 124168-73-6

  • USD $ 1.9-2.9 / Gram

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  • 124168-73-6 Structure

  • Basic information

    1. Product Name: MMP INHIBITOR I
    2. Synonyms: 4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH;METALLOPROTEASE INHIBITOR 1;MATRIX METALLOPROTEINASE INHIBITOR I;H-4-ABZ-GLY-PRO-D-LEU-D-ALA-NHOH;FN-439;MMP INHIBITOR 1;MMP INHIBITOR I;P-AMINOBENZOYL-GLY-PRO-D-LEU-D-ALA HYDROXAMIC ACID
    3. CAS NO:124168-73-6
    4. Molecular Formula: C23H34N6O6
    5. Molecular Weight: 490.55
    6. EINECS: N/A
    7. Product Categories: Inhibitor of human matrix metalloproteinases.
    8. Mol File: 124168-73-6.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: solid
    5. Density: 1.288 g/cm3
    6. Refractive Index: 1.582
    7. Storage Temp.: −20°C
    8. Solubility: H2O: 1 mg/mL
    9. PKA: 9.34±0.40(Predicted)
    10. CAS DataBase Reference: MMP INHIBITOR I(CAS DataBase Reference)
    11. NIST Chemistry Reference: MMP INHIBITOR I(124168-73-6)
    12. EPA Substance Registry System: MMP INHIBITOR I(124168-73-6)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 124168-73-6(Hazardous Substances Data)

124168-73-6 Usage

Uses

Used in Biomedical Research:
MMP Inhibitor I is used as a research tool for studying the role of MMPs in various biological processes, such as cancer progression, wound healing, and tissue remodeling. Its effectiveness in inhibiting MMP enzymes allows researchers to investigate the consequences of MMP inhibition on these processes and explore potential therapeutic applications.
Used in Cancer Therapy:
MMP Inhibitor I is used as a potential therapeutic agent for cancer treatment. Its ability to inhibit MMPs can help prevent the breakdown of the extracellular matrix, which is often associated with tumor invasion and metastasis. By inhibiting MMPs, MMP Inhibitor I may help slow down cancer progression and improve the effectiveness of other cancer treatments.
Used in Wound Healing Applications:
MMP Inhibitor I is used as a potential therapeutic agent for promoting wound healing. MMPs play a crucial role in the wound healing process, and their dysregulation can lead to impaired healing. By inhibiting MMPs, MMP Inhibitor I may help regulate the wound healing process and improve the outcomes for patients with chronic wounds or those recovering from surgery.
Used in Tissue Engineering and Regenerative Medicine:
MMP Inhibitor I is used as a component in tissue engineering and regenerative medicine strategies. Its ability to modulate MMP activity can help control the remodeling of extracellular matrices, which is essential for the successful integration of engineered tissues and the regeneration of damaged tissues. This makes MMP Inhibitor I a valuable tool in the development of advanced therapies for tissue repair and regeneration.

Check Digit Verification of cas no

The CAS Registry Mumber 124168-73-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,4,1,6 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 124168-73:
(8*1)+(7*2)+(6*4)+(5*1)+(4*6)+(3*8)+(2*7)+(1*3)=116
116 % 10 = 6
So 124168-73-6 is a valid CAS Registry Number.
InChI:InChI=1/C23H34N6O6/c1-13(2)11-17(22(33)26-14(3)20(31)28-35)27-23(34)18-5-4-10-29(18)19(30)12-25-21(32)15-6-8-16(24)9-7-15/h6-9,13-14,17-18,35H,4-5,10-12,24H2,1-3H3,(H,25,32)(H,26,33)(H,27,34)(H,28,31)/t14-,17-,18+/m1/s1

124168-73-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid

1.2 Other means of identification

Product number -
Other names 1-[2-[(4-aminobenzoyl)amino]acetyl]-N-[1-[[1-(hydroxyamino)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:124168-73-6 SDS

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