1241725-70-1

Basic information

• Product Name: 1-N-Boc-4,4-difluoropiperidine-3-carboxylic acid ethyl ester
• CAS NO: 1241725-70-1
• Molecular Weight: 293.311
• Mol File: 1241725-70-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-N-Boc-4,4-difluoropiperidine-3-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-N-Boc-4,4-difluoropiperidine-3-carboxylic acid ethyl ester(1241725-70-1)
• EPA Substance Registry System: 1-N-Boc-4,4-difluoropiperidine-3-carboxylic acid ethyl ester(1241725-70-1)

Safety Data

• Hazardous Substances Data: 1241725-70-1(Hazardous Substances Data)

Usage

Structure

1-N-Boc-4,4-difluoropiperidine-3-carboxylic acid ethyl ester

Type

Chemical compound

Use in organic synthesis and pharmaceutical research

Commonly used as a building block in the development of pharmaceuticals and organic compounds

Pharmacological activities

Demonstrated pharmacological activities and shown promising results in various medicinal applications

Potential use in the treatment of various diseases and conditions

Has been studied for its potential use in the treatment of various diseases and conditions.

Upstream product

• 98977-34-5 1-tert-butyl 3-ethyl 4-oxopiperidine-1,3-dicarboxylate 

Relevant articles and documents

Method for synthesizing beta-difluorocarboxylic acid from beta-keto ester

The invention relates to a method for synthesizing a beta-difluorocarboxylic acid compound from beta-keto ester, to solve the technical problems that the yield is low and the production cannot be enlarged in most methods at present. According to the technical scheme of the invention, the method for synthesizing the beta-difluorocarboxylic acid from the beta-keto ester is characterized by comprising the following steps: carrying out a reaction between beta-keto acid ester, which is used as a raw material easily available in the market, and SF4 in the presence of HF to generate beta-difluorocarboxylic ester, and hydrolyzing the beta-difluorocarboxylic ester under an acidic condition to obtain the beta-difluorocarboxylic acid. The molecules and derivatives thereof involved in the invention may be involved in synthesis of an inhibitor of phosphodiesterase (PDEs), particularly PDE2.