1241783-23-2

Upstream product

• 276244-09-8 (+)-(3R,4S)-4-[(S)-2,2-dimethyl-1,3-dioxolan-4-yl]-3-hydroxy-3-(1-methyl-1,2-propadienyl)-1-(p-methoxyphenyl)-2-azetidinone 

Downstream Products

• 1347748-76-8 C₂₆H₂₉NO₅ 

Relevant academic research and scientific papers

Controlled rearrangement of lactam-tethered allenols with brominating reagents: A combined experimental and theoretical study on α-versus β-keto lactam formation

N-Bromosuccinimide (NBS) smoothly promotes the ring expansion of lactam-tethered allenols to efficiently afford cyclic α- or β-ketoamides with good yields and high chemo-, regio-, and diastereoselectivity, through controlled C-C bond cleavage of the β- or

Divergent reactivity of 2-azetidinone-tethered allenols with electrophilic reagents: Controlled ring expansion versus spirocyclization

A dual reactivity of 2-azetidinone-tethered allenols may occur by judicious choice of the electrophilic reagents, namely halogenating versus selenating reagents. Using common substrates, structurally different compounds, namely tetramic acids (from N-bromosuccinimide) or spirocyclic seleno-ss-lactams (from N-phenylselenophthalimide), can be readily synthesized by these divergent protocols.