1241859-88-0Relevant articles and documents
CuO/CNTs-catalyzed heterogeneous process: A convenient strategy to prepare furan derivatives from electron-deficient alkynes and α-hydroxy ketones
Cao, Hua,Jiang, Huan-Feng,Zhou, Xiao-Song,Qi, Chao-Rong,Lin, Yuan-Guang,Wu, Jian-Yong,Liang, Qi-Mei
supporting information, p. 2710 - 2714 (2012/11/07)
As heterogeneous catalysts and nanoparticle support materials, CNTs have attracted great interest in organic chemistry. This paper reports facile CuO/CNTs-catalyzed cyclization to form furan derivatives from electron-deficient alkynes and α-hydroxy ketones. It represents a facile synthetic route, and the eco-friendly catalyst can be easily separated by filtration and reused.
Transition-metal-catalyzed domino reactions: Efficient one-pot regiospecific synthesis of highly functionalized polysubstituted furans from electron-deficient alkynes and 2-Yn-1-ols
Cao, Hua,Jiang, Huanfeng,Huang, Huawen
, p. 1019 - 1036 (2011/05/14)
Based on the reactive behavior of different transition-metal catalysts, three methods for the synthesis of highly functionalized polysubstituted furan derivatives are presented: (i) copper(I) iodide catalyzed regiospecific synthesis of furan aldehydes/ketones from alkynols and diethyl but-2-ynedioate under atmospheric pressure; (ii) nano-Cu-catalyzed domino process for the regioselective synthesis of -carbonylfurans from readily accessible starting materials; (iii) silver-catalyzed one-pot cyclization in toluene at 50 C for the synthesis of furan derivatives. It was notably that all the domino reactions were smooth under mild conditions with commercially available catalysts, and afforded highly functionalized furans in moderate to good yields. As we know, furans derivatives are extremely useful organic molecules used as synthetic building blocks for the synthesis of more elaborate heterocyclic compounds. Georg Thieme Verlag Stuttgart.
Ruthenium-catalyzed coupling reaction of 2,3,5-trisubstituted furans with aryl halides through C-H bond cleavages
Cao, Hua,Zhan, Haiying,Shen, Dongsheng,Zhao, Hong,Liu, Yi
experimental part, p. 3086 - 3090 (2011/09/16)
A variety of functionalized furans were synthesized by way of a ruthenium-catalyzed coupling reaction of 2,3,5-trisubstituted furans with aryl halides through C-H bond cleavages. The feature of the reaction was facilitative preparation of furan derivative