1241896-19-4

Basic information

• Product Name: α-methoxy-triethyl[(2E)-3-phenyl-2-propenyl]phosphonium bromide
• Synonyms: α-methoxy-triethyl[(2E)-3-phenyl-2-propenyl]phosphonium bromide
• CAS NO: 1241896-19-4
• Molecular Weight: 345.26
• Mol File: 1241896-19-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: α-methoxy-triethyl[(2E)-3-phenyl-2-propenyl]phosphonium bromide(CAS DataBase Reference)
• NIST Chemistry Reference: α-methoxy-triethyl[(2E)-3-phenyl-2-propenyl]phosphonium bromide(1241896-19-4)
• EPA Substance Registry System: α-methoxy-triethyl[(2E)-3-phenyl-2-propenyl]phosphonium bromide(1241896-19-4)

Safety Data

• Hazardous Substances Data: 1241896-19-4(Hazardous Substances Data)

Upstream product

• 15647-86-6 triethylphosphine hydrobromide 
• 4364-06-1 (E)-cinnamaldehyde dimethylacetal 

Downstream Products

• 112856-80-1 (E)-ethyl 3-methoxy-3-((E)-styryl)acrylate 

Relevant articles and documents

Discovery of a new class of cinnamyl-triazole as potent and selective inhibitors of aromatase (cytochrome P450 19A1)

Synthesis of a novel class of natural product inspired cinnamyl-containing 1,4,5-triazole and the potent inhibition of human aromatase (CYP 450 19A1) by select members is described. Structure-activity data generated provides insights into the requirements for potency particularly the inclusion of an aryl bromide or chloride residue as a keto-bioisostere.