1241905-70-3Relevant articles and documents
Synthesis ofN-alkylated lipopeptides and their application as organocatalysts in asymmetric Michael addition in aqueous environments
Corrêa, Arlene G.,Delgado, José A. C.,Fernandes, Vitor A.,Paix?o, Márcio W.,Vicente, Fidel E. M.,de la Torre, Alexander F.
supporting information, p. 14050 - 14057 (2021/08/16)
A library ofN-alkylated lipopeptide organocatalysts were synthesized through an isocyanide-based multicomponent reaction. Various structural motifs were tunably introduced on the catalyst backbone with the aim of incorporating amphiphilic features. Conseq
Organocatalytic asymmetric Michael addition of aldehydes and ketones to nitroalkenes catalyzed by adamantoyl L-prolinamide
Wang, Yongchao,Li, Dong,Lin, Jun,Wei, Kun
, p. 5863 - 5874 (2015/03/05)
A series of adamantoyl l-prolinamides have been synthesized. These compounds have been found to be highly efficient organocatalysts for the Michael addition of aldehydes and ketones to nitroalkenes. Under the optimized reaction conditions, the correspondi
Aromatic l-prolinamide-catalyzed asymmetric Michael addition of aldehydes to nitroalkenes
Wang, Yongchao,Lin, Jun,Wei, Kun
, p. 1599 - 1604 (2015/02/02)
Two chiral aromatic l-prolinamides were synthesized in high overall yield (95%) from N-Boc-l-proline and served as organocatalysts in asymmetric Michael reactions of aldehydes to nitroalkenes. Under the optimized reaction conditions, (S)-N-tritylpyrrolidi
Epiandrosterone-derived prolinamide as an efficient asymmetric catalyst for Michael addition reactions of aldehydes to nitroalkenes
Wang, Yongchao,Ji, Shen,Wei, Kun,Lin, Jun
, p. 30850 - 30856 (2014/08/05)
Epiandrosterone derivatives-organocatalyzed asymmetric Michael addition of aldehydes to nitroalkenes was investigated. Among the various catalysts, a novel type of epiandrosterone-derived l-prolineamide catalyst was synthesized and exhibited better perfor
Asymmetric Michael reaction catalyzed by proline lithium salt: Efficient synthesis of L-proline and isoindoloisoquinolinone derivatives
Xu, Kun,Zhang, Sheng,Hu, Yanbin,Zha, Zhenggen,Wang, Zhiyong
supporting information, p. 3573 - 3578 (2013/03/29)
Lithium makes it possible: The enantioselective Michael addition of aldehydes to nitroalkenes was catalyzed by the readily available proline lithium salt. Remarkably, the asymmetric Michael reaction was scaled up to 50 mmol with 23:1 d.r. and 90 % ee. Cop
Prolylprolinol-catalyzed asymmetric michael addition of aliphatic aldehydes to nitroalkenes
Lu, Dengfu,Gong, Yuefa,Wang, Weizhou
supporting information; experimental part, p. 644 - 650 (2010/06/20)
Several novel prolylprolinol catalysts have been designed and synthesized. This type of compound showed high catalytic efficiency on pro-moting the direct addition of unmodified aldehydes to nitroalkenes. Among the catalysts surveyed, the least bulky memb