1241906-04-6

Basic information

• Product Name: 1,1,1-trifluoro-5-[(methoxy)methoxy]-5-phenyl-4-(p-toluenesulfonyloxy)penta-2,3-diene
• Synonyms: 1,1,1-trifluoro-5-[(methoxy)methoxy]-5-phenyl-4-(p-toluenesulfonyloxy)penta-2,3-diene
• CAS NO: 1241906-04-6
• Molecular Weight: 428.429
• Mol File: 1241906-04-6.mol

Chemical Properties

• CAS DataBase Reference: 1,1,1-trifluoro-5-[(methoxy)methoxy]-5-phenyl-4-(p-toluenesulfonyloxy)penta-2,3-diene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1,1-trifluoro-5-[(methoxy)methoxy]-5-phenyl-4-(p-toluenesulfonyloxy)penta-2,3-diene(1241906-04-6)
• EPA Substance Registry System: 1,1,1-trifluoro-5-[(methoxy)methoxy]-5-phenyl-4-(p-toluenesulfonyloxy)penta-2,3-diene(1241906-04-6)

Safety Data

• Hazardous Substances Data: 1241906-04-6(Hazardous Substances Data)

Upstream product

• 1241905-97-4 1,1,1-trifluoro-5-[(methoxy)methoxy]-5-phenyl-4-(p-toluenesulfonyloxy)pent-2-yne 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant articles and documents

Facile conversion of CF3-containing propargylic alcohol derivatives via the corresponding allenes

Empirical information on the acidity of the propargylic proton from our previous work allowed us to develop novel synthetic transformations of readily available terminally trifluoromethylated propargylic alcohols 1 into the corresponding allenyl tosylates 3a, 1-tosyloxy- or 1-acyloxy-4,4,4- trifluorobutan-2-ones 4, and 2-(2,2,2-trifluoroethyl)prop-2-en-1-ones 5, which was enabled by such common bases as NaOH and tertiary amines for affecting ready abstraction of this proton.

Divergent preparation of allenyl tosylates and α-tosyloxy ketones by facile and efficient isomerization of CF3-containing propargylic tosylates

Treatment of trifluoromethylated propargylic tosylates with hydroxides in a water-organic biphasic solvent system efficiently led to isomerization to allenyl tosylates or hydration to α-tosyloxy ketones at room temperature, just by selection of appropriat