1241908-23-5Relevant academic research and scientific papers
Ligand-free and heterogeneous palladium on carbon-catalyzed hetero-suzuki-miyaura cross-coupling
Kitamura, Yoshiaki,Sako, Satoko,Tsutsui, Azusa,Monguchi, Yasunari,Maegawa, Tomohiro,Kitade, Yukio,Sajiki, Hironao
, p. 718 - 730 (2010)
A ligand-free and heterogeneous palladium on carbon (Pd/C)-catalyzed hetero-SuzukiMiyaura coupling reaction has been developed. The protocol enables the construction of both heterocyclic-alicyclic and heterocyclic-heterocyclic biaryl derivatives in good to excellent yields. Furthermore, Pd/C could be reused. The time-course study clarified that palladium was leached into the reaction media as the reaction proceeded and then completely deposited on the carbon support.
