1241921-39-0Relevant articles and documents
5-Stabilized phosphatidylinositol 3,4,5-trisphosphate analogues bind Grp1 PH, inhibit phosphoinositide phosphatases, and block neutrophil migration
Zhang, Honglu,He, Ju,Kutateladze, Tatiana G.,Sakai, Takahiro,Sasaki, Takehiko,Markadieu, Nicolas,Erneux, Christophe,Prestwich, Glenn D.
scheme or table, p. 388 - 395 (2010/12/19)
Metabolically stabilized analogues of PtdIns(3,4,5)P3 have shown long-lived agonist activity for cellular events and selective inhibition of lipid phosphatase activity. We describe an efficient asymmetric synthesis of two 5-phosphatase-resistan
