1241941-33-2

Basic information

• Product Name: pyridin-4-yl[2-(trifluoromethyl)phenyl]methanol
• CAS NO: 1241941-33-2
• Molecular Weight: 253.224
• Mol File: 1241941-33-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: pyridin-4-yl[2-(trifluoromethyl)phenyl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: pyridin-4-yl[2-(trifluoromethyl)phenyl]methanol(1241941-33-2)
• EPA Substance Registry System: pyridin-4-yl[2-(trifluoromethyl)phenyl]methanol(1241941-33-2)

Safety Data

• Hazardous Substances Data: 1241941-33-2(Hazardous Substances Data)

Upstream product

• 872-85-5 pyridine-4-carbaldehyde 
• 392-83-6 o-trifluoromethylphenyl bromide 

Relevant articles and documents

MgCl2-accelerated addition of functionalized organozinc reagents to aldehydes, ketones, and carbon dioxide

Figure Presented Pump it up! The sluggish reactivity of organozinc reagents in additions to aldehydes, ketones, and CO2 can be increased by MgCl2, which is usually generated in the preparation of the zinc reagent. The direct reaction with CO2, in particular, opens an expeditious route to phenylacetic acid derivatives, as demonstrated in a short synthesis of ibuprofen (see scheme).