1241978-14-2Relevant academic research and scientific papers
PEG 400 as a reusable solvent for 1,4-dipolar cycloadditions via a three-component reaction
Reddy, B.V. Subba,Somashekar,Reddy, A. Mallikarjun,Yadav,Sridhar, Balasubramanian
, p. 2069 - 2074 (2010)
Isocyanides, dialkyl acetylenedicarboxylates, and ,-unsaturated aldehydes undergo smooth condensation in poly(ethylene glycol) (PEG 400) to afford the corresponding styrylfuran derivatives in good yields. This method provides a convenient route for a wide range of styrylfurans in a one-pot operation via a three-component reaction. The solvent can be recycled and reused for further reactions. Georg Thieme Verlag Stuttgart.
