1242020-48-9Relevant academic research and scientific papers
Synthesis of Dibenzo[ d, f][1,3]Diazepines via Elemental Sulfur-Mediated Cyclocondensation of 2,2′-Biphenyldiamines with 2-Chloroacetic Acid Derivatives
Tikhonova, Tatyana A.,Lyssenko, Konstantin A.,Zavarzin, Igor V.,Volkova, Yulia A.
, p. 15817 - 15826 (2019)
The three-component reaction of 2,2′-biphenyldiamines with 2-chloroacetic acid derivatives and elemental sulfur was developed for the practical synthesis of unknown 2-carboxamide-substituted dibenzo[d,f][1,3]diazepines. This protocol is distinguished by efficiency in water and good tolerance to functional groups and can be adapted to a large-scale synthesis. The chemoselective preparation of a variety of 2-S,N,O-substituted dibenzo[d,f][1,3]diazepines was accomplished using the developed method.
Sulfur-mediated synthesis of unsymmetrically substituted: N -aryl oxalamides by the cascade thioamidation/cyclocondensation and hydrolysis reaction
Ilment, Nikita V.,Lyssenko, Konstantin A.,Tikhonova, Tatyana A.,Volkova, Yulia A.,Zavarzin, Igor V.
, p. 5050 - 5060 (2020/07/30)
A facile and straightforward synthesis of unsymmetrically substituted N-aryl oxalamides from 2,2′-biphenyldiamines, 2-chloroacetic acid derivatives, elemental sulfur, and water has been developed. This protocol is distinguished by efficiency in water under metal-free conditions for N-aryl oxalamides bearing a side-chain NH2-group; it can be adapted for scale-up synthesis. The scope and limitations of this transformation have been investigated.
Synthesis and reactivity of monothiooxamides of the aminonitroarene series
Yarovenko,Polushina,Levchenko,Zavarzin,Krayushkin,Kotovskaya,Charushin
, p. 1276 - 1280 (2010/10/04)
Monothiooxamides containing aminonitrobenzene and aminonitropyridine fragments have been synthesized. A possibility to synthesize thioesters and fused imidazole and diazepine derivatives on their basis has been demonstrated. ; 2009 Springer Science+Busine
