1242046-45-2Relevant academic research and scientific papers
Highly enantioselective Michael addition reactions of 3-substituted benzofuran-2(3H)-ones to chalcones catalyzed by a chiral alkyl-substituted thiourea
Li, Xin,Xi, Zhiguo,Luo, Sanzhong,Cheng, Jin-Pei
supporting information; experimental part, p. 1097 - 1101 (2010/06/20)
A highly enantioselective Michael addition of 3-substituted benzofuran-2(3H)-ones to chalcones catalyzed by a chiral bifunctional thiourea was developed. Several chiral 3,3′-substituted benzofuran-2(3H)-ones derivatives, bearing adjacent quaternary-tertiary stereocenters, were efficiently synthesized with excellent enantioselectivities.
