1242057-11-9Relevant academic research and scientific papers
4-Hydroxy-2-quinolones 173. 1-R-3-(2-diethylamino- ethyl)-1H-quinazoline- 2,4-dione hydrochlorides as potential local anesthetic agents
Ukrainets,Kravtsova,Tkach,Mamchur,Kovalenko, E. Yu.
, p. 96 - 105 (2010)
Different variants of the preparation and procedures in the synthesis of a series of 1-R-3-(2-dialkyl-aminoethyl)-1H-quinazoline-2,4-dione hydrochlorides having a structural similarity to the 4-hydroxy-2-quinolinone anesthetic chinoxicaine are discussed. A comparative analysis of the biological properties of the synthesized compounds and the known local anesthetics chinoxicaine and lidocaine is reported.
