1242068-64-9Relevant academic research and scientific papers
Total synthesis of pareitropone via radical anion coupling
Hong, Suk-Koo,Kim, Hyeonjeong,Seo, Youngran,Lee, Sang Hyup,Cha, Jin Kun,Kim, Young Gyu
supporting information; experimental part, p. 3954 - 3956 (2010/11/04)
A concise (9-step) synthesis of the tropoloisoquinoline alkaloid pareitropone has been achieved starting from 2-bromoisovanillin. The key step features oxidative cyclization of a readily available phenolic nitronate for the convenient construction of the fused tropone ring. This work underscores the synthetic utility of intramolecular oxidative coupling reactions of phenolic nitronates.
