1242072-82-7Relevant academic research and scientific papers
Beyond acid strength in zeolites: Soft framework counteranions for stabilization of carbocations on zeolites and its implication in organic synthesis
Cabrero-Antonino, Jose R.,Leyva-Prez, Antonio,Corma, Avelino
supporting information, p. 5658 - 5661 (2015/10/12)
The generation of a carbocation with an acid depends not only on the acid strength but also on the ability of the counteranion to stabilize the positive charge left behind. Here we report that despite their relatively weak acidity, zeolites are able to ge
Bronsted acid catalyzed cyclization of propargylic alcohols with thioamides. Facile synthesis of Di- and trisubstituted thiazoles
Zhang, Xiaoxiang,Teo, Wan Teng,Sally,Chan, Philip Wai Hong
experimental part, p. 6290 - 6293 (2010/11/18)
Figure presented. A general and efficient method to prepare 2,4-di- and trisubstituted thiazoles via p-TsOH·H2O-catalyzed cyclization of trisubstituted propargylic alcohols with thioamides is described. The reaction was accomplished in moderate to excellent product yields under mild conditions that did not require the exclusion of air and moisture and offers an operationally simplistic and convenient route to this synthetically useful aromatic heterocycle.
