1242104-68-2Relevant academic research and scientific papers
Carbonic Anhydrases inhibitory effects of new benzenesulfonamides synthesized by using superacid chemistry
Liu, Fei,Martin-Mingot, Agnès,Lecornué,Jouannetaud, Marie-Paule,Maresca, Alfonso,Thibaudeau, Sebastien,Supuran, Claudiu T.
, p. 886 - 891 (2013/02/23)
A series of benzofused sultams and fluorinated benzenesulfonamides were synthesized in superacid HF/SbF5 from simple N-allylic derivatives. Almost all of these original compounds showed micromolar inhibitory activities against carbonic anhydrases I and II
Superacid mediated reactions applied to 4-aminobenzofused sultams and fluorinated 4-aminobenzene sulfonamides synthesis
Liu, Fei,Musadji, Neil Y.,Lecornué, Frédéric,Jouannetaud, Marie-Paule,Thibaudeau, Sébastien
scheme or table, p. 7112 - 7118 (2010/10/02)
A novel series of 4-aminobenzofused sultams was prepared using an efficient synthetic procedure based on superacid mediated reactions followed either by copper-catalyzed coupling or SNAr reactions. The synthetic potential of the method toward the divergent synthesis of novel potent bioactive (fluorinated) aminobenzofused sultams and fluorinated 4-aminobenzene sulfonamides was shown, making it a new valuable process to synthesize a large diversity of compounds in bioactive 4-aminobenzene sulfonamide family.
