1242308-74-2

Upstream product

• 1242308-73-1 (R)-4-((R)-(3-(benzyloxymethyl)oxiran-2-yl)fluoromethyl)-2,2-dimethyl-1,3-dioxolane 
• 1456889-96-5 (R)-4-((R)-((2S,3R)-3-((benzyloxy)methyl)oxiran-2-yl)fluoromethyl)-2-2dimethyl-1,3-dioxolane 
• 1456889-95-4 (2R,3S)-3-(((R)-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)fluoromethyl)oxiran-2-yl)methanol 
• 1456889-94-3 (S,E)-4-((R)-4-2,2-dimethyl-1,3-dioxolan-4-yl)-4-fluorobut-2-en-1-ol 
• 1456889-93-2 (S,E)-ethyl 4-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-4-fluorobut-2-enoate 
• 1456889-92-1 (4S,5R,E)-ethyl 4-fluoro-5,6-dihydroxyhex-2-enoate 
• 1456889-91-0 (E)-ethyl 3-((2R,3R)-3-(((tert-butyldimethylsilyl)oxy)methyl)oxiran-2-yl)acrylate 

Downstream Products

• 1242308-76-4 (R)-4-((1R,2R,3S)-4-(benzyloxy)-1,2,3-trifluorobutyl)-2,2-dimethyl-1,3-dioxolane 

Relevant academic research and scientific papers

Fluorosugars: An improved synthesis of the 2,3,4-trideoxy-2,3,4-trifluoro hexose analogue of d-glucose

An improved synthetic route for the synthesis of the 2,3,4-trideoxy-2,3,4- trifluoro hexose analogue of d-glucose has been developed. The newly reported synthesis features improved fluorination reactions and simpler chromatographic separations.

Fluorosugars: Synthesis of the 2,3,4-trideoxy-2,3,4-trifluoro hexose analogues of d-glucose and d-altrose and assessment of their erythrocyte transmembrane transport

The 2,3,4-trideoxy-2,3,4-trifluoro hexose analogues of d-glucose and d-altrose were prepared and characterised and these novel sugar analogues were explored by 2D-19F-EXSY NMR for their potential to cross erythrocyte (red blood cell) membranes,