1242316-85-3Relevant academic research and scientific papers
Efficient synthesis of a new type of baylis-hillman adducts and their stereoselective bromination
Zhong, Weihui,Jiang, Lingbo,Guo, Baoming,Wu, Yaotiao,Hong, Lingjuan,Chen, Yanhui
, p. 2441 - 2456 (2010)
A new type of Baylis-Hillman adducts derived from chlorovinyl aldehydes were prepared via Vilsmeier reaction of ketones with a bis(trichloromethyl) carbonate (BTC)/DMF system to construct chlorovinyl aldehydes, followed by sonochemical Baylis-Hillman reaction under solvent-free conditions. The stereoselective bromination of these new compounds with a Br2-Ph3P system has been achieved efficiently with good to excellent yields under mild conditions. Copyright Taylor & Francis Group, LLC.
