1242338-65-3Relevant academic research and scientific papers
Synthesis of functionalized 3-hydroxypiperidines
Wijdeven, Marloes A.,Van Delft, Floris L.,Rutjes, Floris P.J.T.
experimental part, p. 5623 - 5636 (2010/10/02)
The synthetic versatility of three chemoenzymatically prepared hydroxypiperidine building blocks has been explored, resulting in a library of enantiopure functionalized piperidines. Key steps involved N-acyliminium ion-mediated CC-bond formation and cross-metathesis reactions, after which full deprotection led to the set of free 3-hydroxypiperidines.
