1242419-39-1Relevant articles and documents
Novel Axially Chiral Ligand-Enabled Copper-Catalyzed Asymmetric Oxidative Coupling of 2-Naphthols for the Synthesis of 6,6′-Disubstituted BINOLs
Wang, Pengyang,Cen, Shouyi,Gao, Jun,Shen, Ahui,Zhang, Zhipeng
, p. 2321 - 2326 (2022/04/07)
Novel axially chiral ligands have been designed and synthesized by merging the chelating picolinic acid with substituted BINOLs. The in-situ-prepared copper catalysts from the ligands and CuI enable the asymmetric oxidative coupling of 2-naphthols, afford
Efficient synthesis of 3,3'-diaryl binaphthol through a one-step method
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Paragraph 0042-0044, (2018/07/30)
The invention relates to a class of catalysis reactions of binaphthol and halogenated aromatic hydrocarbons, particularly to efficient preparation of 3,3'-diaryl binaphthol and 3-Bulkyaryl binaphtholthrough a one-step method, and belongs to the technical field of asymmetric catalysis. A purpose of the present invention is to provide a simple and practical method for preparing 3,3'-diaryl binaphthol through a one-step reaction of inexpensive BINOL and a brominated aromatic hydrocarbon reagent, and is further to provide a simple and rapid method for conveniently preparing 3-aryl binaphthol withhigh steric hindrance.
Expedient BINOL derivative arylations
Albini, Mathieu,Taillier, Catherine,Dalla, Vincent,Blanchet, Jér?me,Rouden, Jacques
, p. 6420 - 6422 (2014/12/10)
A dramatic improvement of our previous methodology based on a Suzuki-Miyaura cross-coupling to access 3,3′-disubstituted H8-BINOLs using microwave heating is reported herein. These new conditions represent a large gain in term of atom-economy, reaction time, catalyst loading, and excess of reagents employed.