1242421-77-7

Basic information

• Product Name: (11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide
• Synonyms: (11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide;(S)-3,3′-Bis[3,5-bis(trifluoromethyl)phenyl]-1,1′-binaphthyl-2,2′-disulfonimide;(11bS)- 2,6-bis[3,5-bis(trifluoromethyl)phenyl]-3,3,5,5-tetraoxide-Dinaphtho[2,1-d:1',2'f][1,3,2]dithiazepine;(S)-3,3'-Bis[3,5-bis(trifluoromethyl)phenyl]-1,1'-binaphthyl-2,2'-disulfonimide 95%
• CAS NO: 1242421-77-7
• Molecular Formula: C36H17F12NO4S2
• Molecular Weight: 819.64
• Mol File: 1242421-77-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 325-330°C
• Appearance: /
• CAS DataBase Reference: (11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide(CAS DataBase Reference)
• NIST Chemistry Reference: (11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide(1242421-77-7)
• EPA Substance Registry System: (11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide(1242421-77-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 1242421-77-7(Hazardous Substances Data)

Usage

Uses

Used in Chiral Bronsted Acid Applications:
(11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide is used as a chiral Br?nsted acid catalyst in Mukaiyama aldol reactions and Friedel-Crafts alkylation of indoles with sulfonyl imines. Its chiral properties enable the enantioselective formation of desired products, making it a valuable tool in asymmetric catalysis.
Used in Asymmetric Catalysis:
In the field of asymmetric catalysis, (11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide serves as a powerful chiral counteranion motif. Its unique structure allows for the selective activation and transformation of substrates, leading to the formation of enantioenriched products.
Used in Pharmaceutical Industry:
(11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide is used as a chiral Br?nsted acid organocatalyst for asymmetric Friedel-Crafts alkylation of indoles with imines. This application is particularly relevant in the pharmaceutical industry, where the development of enantioselective synthetic routes is crucial for the production of chiral drugs with improved efficacy and reduced side effects.
Used in Enantioselective Electrophilic Fluorination and Oxidative Fluorination:
(11bS)-2,6-Bis[3,5-bis(trifluoromethyl)phenyl]dinaphtho[2,1-d:1′,2′-f][1,3,2]dithiazepine 3,3,5,5-tetraoxide is also used in the synthesis of chiral N-fluorodibenzenesulfonimide analogues, which are employed as reagents for enantioselective electrophilic fluorination and oxidative fluorination reactions. These reactions are important for the introduction of fluorine atoms into organic molecules, which can significantly impact the properties and reactivity of the resulting compounds.