124244-35-5Relevant academic research and scientific papers
Radical α-Allylation of Alkyl-Substituted α-(Phenylseleno)cycloalkanones
Toru, Takeshi,Okumura, Tatsuya,Ueno, Yoshio
, p. 1277 - 1280 (1990)
Irradiation and thermal reaction of 3-, 4-, or 6-alkyl-2-(phenylseleno)cycloalkanones with tributyl-2-propenyltin gave 2-allylated products in high yields.Either trans- or cis-selenocycloalkanones afforded the identical distribution of cis- and trans-ally
Highly regioselective alkylation at the more hindered α-site of unsymmetrical ketones by use of their potassium enolates. A comparative study with lithium enolates
Quesnel, Yannick,Bidois-Sery, Laure,Poirier, Jean-Marie,Duhamel, Lucette
, p. 413 - 415 (2007/10/03)
Alkylation of regioisomeric potassium enolates 4 and 6 obtained from corresponding silyl enol ethers 2 and 3 occurs at the most substituted site affording ketones 8. Alkylation of corresponding lithium enolates 5 and 7 occurs at the expected site affording ketones 8 or 9. As an application the one pot synthesis of spiroketones 13 from silyl enol ethers 12 is described.
