1242445-55-1

Basic information

• Product Name: 8-(3-(pyrrolidin-1-ylmethyl)phenyl)-N-(thiazol-2-yl)quinoline-2-carboxamide
• Synonyms: 8-(3-(pyrrolidin-1-ylmethyl)phenyl)-N-(thiazol-2-yl)quinoline-2-carboxamide
• CAS NO: 1242445-55-1
• Molecular Weight: 414.531
• Mol File: 1242445-55-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-(3-(pyrrolidin-1-ylmethyl)phenyl)-N-(thiazol-2-yl)quinoline-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(3-(pyrrolidin-1-ylmethyl)phenyl)-N-(thiazol-2-yl)quinoline-2-carboxamide(1242445-55-1)
• EPA Substance Registry System: 8-(3-(pyrrolidin-1-ylmethyl)phenyl)-N-(thiazol-2-yl)quinoline-2-carboxamide(1242445-55-1)

Safety Data

• Hazardous Substances Data: 1242445-55-1(Hazardous Substances Data)

Upstream product

• 1100095-09-7 3-(pyrrolidin-1-ylmethyl)phenylboronic acid 
• 1242446-36-1 8-bromo-N-(thiazol-2-yl)quinoline-2-carboxamide 

Relevant articles and documents

8-SUBSTITUTED QUINOLINES AND RELATED ANALOGS AS SIRTUIN MODULATORS

Provided herein are 8-substituted quinolines and related analogues as sirtuin-modulating compounds of Structural Formula (I) and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.