1242471-67-5Relevant academic research and scientific papers
Diphenylammonium triflate: A novel and efficient catalyst for synthesis of spiro-heterocyclic compounds
Li, Jianjun,Sun, Jian,Su, Weike
experimental part, p. 314 - 318 (2011/07/07)
A general and practical one-pot synthesis of spiro-heterocyclic compounds using diphenylammonium triflate (DPAT, 5 mol%) as a novel and efficient catalyst is described. The pseudo four-components Biginelli-like reaction of 5,5- dimethyl-1,3-cyclohexanedione, thiourea and aldehydes catalyzed by DPAT in refluxing ethanol produced the corresponding spiro-heterocyclic compounds with moderate to good yields. A possible mechanism is proposed.
