1242592-27-3Relevant academic research and scientific papers
Enantioselective Palladium(II)-Catalyzed Intramolecular Aminoarylation of Alkenes by Dual N?H and Aryl C?H Bond Cleavage
Zhang, Wen,Chen, Pinhong,Liu, Guosheng
, p. 5336 - 5340 (2017/04/27)
An asymmetric palladium-catalyzed intramolecular oxidative aminoarylation of alkenes has been developed with quinoline–oxazoline chiral ligands and Ag2CO3 as the oxidant. Various indolines containing a quaternary stereogenic center were synthesized in high yield with excellent enantioselectivity. Preliminary mechanistic studies suggest that the addition of a catalytic amount of phenylglyoxylic acid significantly accelerates the reaction and slightly enhances the enantioselectivity.
Hydriodic acid-mediated cyclization of a-substituted secondary 2-ethenylbenzamides: Synthesis of 2-substituted 2,3-dihydro-3,3-dimethyl-1H- isoindol-1-ones and 3,3-disubstituted (E)-1-(arylimino)-1,3- dihydroisobenzofurans
Kobayashi, Kazuhiro,Fujita, Seiki,Nakai, Daisuke,Fukumoto, Shogo,Fukamachi, Shuhei,Konishi, Hisatoshi
scheme or table, p. 1274 - 1280 (2010/09/07)
A new and facile method for the preparation of 2-substituted 2,3-dihydro-3,3-dimethyl-1H-isoindol-1-ones 3 and 3,3-disubstituted (E)-1-(arylimino)-1,3-dihydroisobenzofurans 6 has been developed. Thus, treatment of N-alkyl(or aryl)-2-(1-methylethen-1-yl)be
