1242614-51-2Relevant academic research and scientific papers
A novel synthesis of 1,5-disubstituted fluorinated tetrazoles from 1,1-difluoroazides
Polivanova, Anna G.,Shkavrov, Sergey V.,Churakov, Andrei V.,Lermontov, Anatoly S.,Lermontov, Sergey A.
scheme or table, p. 4205 - 4207 (2010/09/12)
A new one-step reaction between 1,1-difluoroazides and primary amines is reported as an efficient synthetic approach for tetrazole formation. Examples include the syntheses of fluorine-containing 1,5-substituted tetrazoles from three fluorinated azide precursors and various amines. Greater substituent diversity in comparison with conventional methods is achieved.
