1242618-38-7Relevant articles and documents
Synthesis of isomeric fluoronitrobenzene-sulfonyl chlorides
Zhersh, Sergey,Lukin, Oleg,Matvienko, Vitaly,Tolmachev, Andrey
, p. 5982 - 5986 (2010)
The synthesis of five hitherto unknown isomeric fluoronitrobenzenesulfonyl chlorides is described. The compounds are prepared from difluoronitrobenzenes by a two-step procedure. In the first step the starting compounds undergo a regioselective reaction with phenylmethanethiol giving rise to the corresponding thioethers. The oxidative cleavage of the latter with chlorine results in the sulfonyl chlorides in good yields. One example of a threefold sequential functionalization of 2-fluoro-6-nitrobenzenesulfonyl chloride showing the synthetic utility of the title compounds is provided.