124293-27-2Relevant academic research and scientific papers
AN EXPEDITIOUS SYNTHESIS OF 2-DIALKYLAMINO-4-CHLOROPYRIMIDINES FROM SILYLATED PRIMARY ENAMINES AND PHOSGENIMINIUM SALTS
Guillot, Nadine,Janousek, Zdenek,Viehe, Heinz G.
, p. 879 - 886 (2007/10/02)
Trimethylsilyl-protected primary enamines 4 condense with two equivalents of phosgeniminium chloride (PI) to form 2-aza-1,5-dichloropentamethine cyanides 5.This versatile intermediates cyclize upon heating to 2-(dialkylamino)-5-alkyl-6-aryl-4-chloropyrimi
