1242939-75-8Relevant academic research and scientific papers
Total synthesis of the pyranoisoflavone kraussianone 1 and related isoflavones
Selepe, Mamoalosi A.,Drewes, Siegfried E.,Van Heerden, Fanie R.
body text, p. 1680 - 1685 (2011/02/21)
The first total synthesis of the pyranoisoflavone kraussianone 1 (1) is described. The key steps involved the Suzuki-Miyaura reaction for the construction of the isoflavone core and the regioselective formation of the dimethylpyran scaffolds to the phloroglucinol (ring A) and resorcinol (ring B) moieties of kraussianone 1 (1). This route also provided access to the related isoflavones eriosemaone D (2) and genistein (3) via simple structural modifications.
