124294-74-2

Upstream product

• 124294-72-0 4,5-dihydro-6-(4-methoxy-2-methyl-7-quinazolinyl)-5-methyl-3(2H)-pyridazinone 
• 100-46-9 benzylamine 
• 124294-73-1 4,5-dihydro-6-(2-methyl-4-methylamino-7-quinazolinyl)-5-methyl-3(2H)-pyridazinone 
• 124294-91-3 4,5-Dihydro-6-(3-amino-4-cyanophenyl)-5-methyl-3(2H)-pyridazinone 

Relevant academic research and scientific papers

Studies on cardiotonic agents. VII. Potent cardiotonic agent KF15232 with myofibrillar Ca2+ sensitizing effect

A series of novel 4,5-dihydro-5-methyl-6-(2 or 4-substituted 7-quinazolinyl)-3-(2H)-pyridazinones was synthesized and examined for cardiotonic activity in anesthetized dogs. The 4-substituted aminoquinazolines generally showed potent and long-lasting inot

Quinazoline-substituted pyridazinone derivatives having cardiotonic activity

Compounds of the formula STR1 wherein R3 is H or alkyl, Q1 and Q2 are independently hydrogen, alkyl, hydroxyl, alkoxyl, amino, mono or di alkylamino, nitro or halo or pharmaceutically acceptable salts are useful as cardiotonics.