124294-74-2

Upstream product

• 124294-72-0 4,5-dihydro-6-(4-methoxy-2-methyl-7-quinazolinyl)-5-methyl-3(2H)-pyridazinone 
• 100-46-9 benzylamine 
• 124294-91-3 4,5-Dihydro-6-(3-amino-4-cyanophenyl)-5-methyl-3(2H)-pyridazinone 
• 124294-73-1 4,5-dihydro-6-(2-methyl-4-methylamino-7-quinazolinyl)-5-methyl-3(2H)-pyridazinone 

Relevant academic research and scientific papers

Quinazoline-substituted pyridazinone derivatives having cardiotonic activity

Compounds of the formula STR1 wherein R3 is H or alkyl, Q1 and Q2 are independently hydrogen, alkyl, hydroxyl, alkoxyl, amino, mono or di alkylamino, nitro or halo or pharmaceutically acceptable salts are useful as cardiotonics.

Studies on cardiotonic agents. VII. Potent cardiotonic agent KF15232 with myofibrillar Ca2+ sensitizing effect

A series of novel 4,5-dihydro-5-methyl-6-(2 or 4-substituted 7-quinazolinyl)-3-(2H)-pyridazinones was synthesized and examined for cardiotonic activity in anesthetized dogs. The 4-substituted aminoquinazolines generally showed potent and long-lasting inot