124312-73-8

Basic information

• Product Name: 2-(AMINOMETHYL)-1-METHYLIMIDAZOLE
• Synonyms: 2-(AMINOMETHYL)-1-METHYLIMIDAZOLE;1-METHYL-2-METHYLAMINO-IMIDAZOLE;(1-METHYL-1H-IMIDAZOL-2-YL)METHANAMINE;1-(1-methyl-1H-imidazol-2-yl)methanamine(SALTDATA: 2HCl);1-Methyl-2-iMidazoleMethanaMine;1H-Imidazole-2-methanamine, 1-methyl-;2-Aminomethyl-1-methyl-1H-imidazol, 98%
• CAS NO: 124312-73-8
• Molecular Formula: C₅H₉N₃
• Molecular Weight: 111.15
• Mol File: 124312-73-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 255.1 °C at 760 mmHg
• Flash Point: 108.1 °C
• Appearance: /
• Density: 1.16 g/cm³
• Vapor Pressure: 0.0166mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 8.03±0.40(Predicted)
• CAS DataBase Reference: 2-(AMINOMETHYL)-1-METHYLIMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(AMINOMETHYL)-1-METHYLIMIDAZOLE(124312-73-8)
• EPA Substance Registry System: 2-(AMINOMETHYL)-1-METHYLIMIDAZOLE(124312-73-8)

Safety Data

• Hazard Codes: C:Corrosive
• Statements: R34:Causes burns.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl
• RIDADR: 2735
• HazardClass: IRRITANT
• PackingGroup: Ⅲ
• Hazardous Substances Data: 124312-73-8(Hazardous Substances Data)

Usage

General Description

2-(Aminomethyl)-1-methylimidazole, also known as AMI, is a chemical compound with the molecular formula C5H9N3. It is a colorless to pale yellow liquid with a strong, amine-like odor. AMI is commonly used as a catalyst in the production of flexible polyurethane foams and resins. It is also utilized as a corrosion inhibitor in the oil and gas industry. Additionally, AMI is used in the synthesis of pharmaceuticals and agrochemicals. Due to its potential adverse health effects, including skin and eye irritation, as well as respiratory and central nervous system effects, proper handling and precautionary measures should be taken when working with 2-(aminomethyl)-1-methylimidazole.

InChI:InChI=1/C5H9N3/c1-8-3-2-7-5(8)4-6/h2-3H,4,6H2,1H3

Upstream product

• 1430413-09-4 1-methyl-1H-imidazole-2-carbaldehyde O-benzyloxime 
• 864913-19-9 2-(1-methyl-1H-imidazol-2-ylmethyl)-isoindol-1,3-dione 
• 13750-81-7 N-methyl-2-imidazolcarboxaldehyde 

Downstream Products

• 1423767-16-1 1-(3-isopropylamino-benzyl)-3-(1-methyl-1H-imidazol-2-ylmethyl)-urea 
• 1131736-18-9 4-amino-3,5-dichloro-N-[(1-methyl-1H-imidazol-2-yl)methyl]benzenesulfonamide 

Relevant articles and documents

A novel synthetic approach towards 2-guanidinomethyl-4(5)- sulfamoylimidazoles

A library of 2-guanidinomethyl-4(5)-sulfamoylimidazoles was synthesised in a convergent manner by introducing a sulfonyl chloride group via a trianion electrophilic sulfinylation of suitably protected 2-guanidinomethyl imidazoles.

BASIC AMINE COMPOUND AND USE THEREOF

Novel amine compounds which are represented by the following formula (1) and efficacious against diseases such as a viral infectious disease with HIV, rheumatism, and cancer metastasis; typically, A 1 and A 2 represent a hydrogen atom or a substitutable monocyclic or polycyclic heteroaromatic ring and W represents a substitutable benzene ring or any group represented by the following formula (10) or (11): where X represents O, CH 2 , C(=O), NR 11 , or CHR 35 and D represents a group represented by the following formula (6): where Q represents a single bond, NR 12 , or a group represented by the formula (13): and Y represents a group represented by the following formula (7) : where z represents a substitutable monocyclic or polycyclic aromatic ring; and B represents -NR 25 R 26 ; and R 1 to R 26 in the above formulae represent a hydrogen atom, an alkyl group, an alkenyl group, or an alkynyl group.

Inhibitors of HIV reverse transcriptase

Novel indole compounds inhibit HIV reverse transcriptase, and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.