124314-07-4

Basic information

• Product Name: (4aR,8R,8aS)-8-Ethyl-2-phenyl-4,4a,8,8a-tetrahydro-pyrano[3,2-d][1,3]dioxine
• CAS NO: 124314-07-4
• Molecular Weight: 246.306
• Mol File: 124314-07-4.mol

Chemical Properties

• CAS DataBase Reference: (4aR,8R,8aS)-8-Ethyl-2-phenyl-4,4a,8,8a-tetrahydro-pyrano[3,2-d][1,3]dioxine(CAS DataBase Reference)
• NIST Chemistry Reference: (4aR,8R,8aS)-8-Ethyl-2-phenyl-4,4a,8,8a-tetrahydro-pyrano[3,2-d][1,3]dioxine(124314-07-4)
• EPA Substance Registry System: (4aR,8R,8aS)-8-Ethyl-2-phenyl-4,4a,8,8a-tetrahydro-pyrano[3,2-d][1,3]dioxine(124314-07-4)

Safety Data

• Hazardous Substances Data: 124314-07-4(Hazardous Substances Data)

Upstream product

• 5987-33-7 4,6-O-benzylidene-D-allal 
• 925-90-6 ethylmagnesium bromide 
• 88095-31-2 1,5-anhydro-4,6-O-benzylidene-2-deoxy-3-O-mesyl-D-ribo-hex-1-enitol 

Relevant articles and documents

Regioselective Methylation of the C-1 and C-3 Positions of 1,5-Anhydro-4,6-O-benzylidene-2-deoxy-3-O-mesyl-D-ribo-hex-1-enitol by the Reaction with Methylmagnesium Bromide or Methyl Cuprates

1,5-Anhydro-4,6-O-benzylidene-2-deoxy-3-O-mesyl-D-ribo-hex-1-enitol reacted with alkylmagnesium bromides (RMgBr: R = C2H5-, (CH3)2CH-, or C2H5(CH3)CH-) to give the corresponding 1-β-C-glycopyranosides and 3-C-alkyl-D-arabino-hex-1-enitols, while the reaction with methylmagnesium bromide afforded 1-α-C- and 1-β-C-methyl-glycosides in a ratio of 1 : 1.5-2.On the other hand, when the reaction was carried out in the presence of CuI or CuBr-S(CH3)2, substitution took place at the C-3 position to afford the corresponding 3-C-methyl-D-arabino-hex-1-enitol.